| Combination of | |
|---|---|
| Ibuprofen | Nonsteroidal anti-inflammatory drug (NSAID) |
| Famotidine | H2 antagonist |
| Clinical data | |
| Trade names | Duexis |
| Other names | HZT-501 |
| AHFS/Drugs.com | Micromedex Detailed Consumer Information |
| License data | |
| Routes of administration | By mouth |
| ATC code | |
| Legal status | |
| Legal status | |
| Identifiers | |
| CAS Number | |
| KEGG | |
Ibuprofen/famotidine, sold under the brand name Duexis, is a fixed-dose combination medication used for the treatment of rheumatoid arthritis and osteoarthritis.[1] It contains ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID) and famotidine, a histamine H2-receptor antagonist.[1]
Ibuprofen/famotidine is available as a generic medication.[2]
References
- 1 2 3 "Duexis- ibuprofen and famotidine tablet, coated". DailyMed. Retrieved 6 August 2021.
- ↑ "Generic Duexis Availability". Drugs.com. 9 March 2023. Retrieved 17 March 2023.
Further reading
- Bello AE (October 2012). "Duexis (ibuprofen 800 mg, famotidine 26.6 mg): a new approach to gastroprotection for patients with chronic pain and inflammation who require treatment with a nonsteroidal anti-inflammatory drug". Therapeutic Advances in Musculoskeletal Disease. 4 (5): 327–39. doi:10.1177/1759720X12444710. PMC 3458616. PMID 23024710.
- Deeks ED (September 2013). "Fixed-dose ibuprofen/famotidine: a review of its use to reduce the risk of gastric and duodenal ulcers in patients requiring NSAID therapy". Clin Drug Investig. 33 (9): 689–97. doi:10.1007/s40261-013-0113-x. PMID 23881568. S2CID 24972423.
External links
- "Famotidine mixture with ibuprofen". Drug Information Portal. U.S. National Library of Medicine.
| pyrazolones / pyrazolidines | |
|---|---|
| salicylates | |
| acetic acid derivatives and related substances | |
| oxicams |
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| propionic acid derivatives (profens) |
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| n-arylanthranilic acids (fenamates) | |
| COX-2 inhibitors (coxibs) | |
| other | |
| NSAID combinations | |
Key: underline indicates initially developed first-in-class compound of specific group; #WHO-Essential Medicines; †withdrawn drugs; ‡veterinary use. | |
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