Iron lung
An Emerson iron lung
SpecialtyPulmonology
ICD-9-CM93.99
MeSHD015919

An iron lung is a type of negative pressure ventilator (NPV), a mechanical respirator which encloses most of a person's body, and varies the air pressure in the enclosed space, to stimulate breathing.[1][2][3][4] It assists breathing when muscle control is lost, or the work of breathing exceeds the person's ability.[1] Need for this treatment may result from diseases including polio and botulism and certain poisons (for example, barbiturates, tubocurarine).

The use of iron lungs is largely obsolete in modern medicine as more modern breathing therapies have been developed[5] and due to the eradication of polio in most of the world.[6] However, in 2020, the COVID-19 pandemic revived some interest in the device as a cheap, readily-producible substitute for positive-pressure ventilators, which were feared to be outnumbered by patients potentially needing temporary artificially assisted respiration.[7][8][9][10]

The iron lung is a large horizontal cylinder designed to stimulate breathing in patients who have lost control of their respiratory muscles. The patient's head is exposed outside the cylinder, while the body is sealed inside. Air pressure inside the cylinder is cycled to facilitate inhalation and exhalation. Devices like the Drinker, Emerson, and Both respirators are examples of iron lungs, which can be manually or mechanically powered. Smaller versions, like the cuirass ventilator and jacket ventilator, enclose only the patient's torso. Breathing in humans occurs through negative pressure, where the rib cage expands and the diaphragm contracts, causing air to flow in and out of the lungs.

The concept of external negative pressure ventilation was introduced by John Mayow in 1670. The first widely used device was the iron lung, developed by Philip Drinker and Louis Shaw in 1928. Initially used for coal gas poisoning treatment, the iron lung gained fame for treating respiratory failure caused by polio in the mid-20th century. John Haven Emerson introduced an improved and more affordable version in 1931. The Both respirator, a cheaper and lighter alternative to the Drinker model, was invented in Australia in 1937. British philanthropist William Morris financed the production of the Both-Nuffield respirators, donating them to hospitals throughout Britain and the British Empire. During the polio outbreaks of the 1940s and 1950s, iron lungs filled hospital wards, assisting patients with paralyzed diaphragms in their recovery.

Polio vaccination programs and the development of modern ventilators have nearly eradicated the use of iron lungs in the developed world. Positive pressure ventilation systems, which blow air into the patient's lungs via intubation, have become more common than negative pressure systems like iron lungs. However, negative pressure ventilation is more similar to normal physiological breathing and may be preferable in rare conditions. As of 2008, around 30 patients in the U.S. were still using iron lungs. In response to the COVID-19 pandemic and the shortage of modern ventilators, some enterprises developed prototypes of new, easily producible versions of the iron lung.

Design and function

Iron lung cylinder (black), patient head exposed through sealed opening. Diaphragm (yellow) mechanically extends/retracts, varying cylinder air pressure, causing patient chest to expand (inhale) (top) and contract (exhaling) (bottom)

The iron lung is typically a large horizontal cylinder in which a person is laid, with their head protruding from a hole in the end of the cylinder, so that their full head (down to their voice box) is outside the cylinder, exposed to ambient air, and the rest of their body sealed inside the cylinder, where air pressure is continuously cycled up and down to stimulate breathing.[1][2][3][11][12]

To cause the patient to inhale, air is pumped out of the cylinder, causing a slight vacuum, which causes the patient's chest and abdomen to expand (drawing air from outside the cylinder, through the patient's exposed nose or mouth, into their lungs). Then, for the patient to exhale, the air inside the cylinder is compressed slightly (or allowed to equalize to ambient room pressure), causing the patient's chest and abdomen to partially collapse, forcing air out of the lungs, as the patient exhales the breath through their exposed mouth and nose, outside the cylinder.[1][2][3][11][12]

Examples of the device include the Drinker respirator, the Emerson respirator, and the Both respirator. Iron lungs can be either manually or mechanically powered, but are normally powered by an electric motor linked to a flexible pumping diaphragm (commonly opposite the end of the cylinder from the patient's head).[2] Larger "room-sized" iron lungs were also developed, allowing for simultaneous ventilation of several patients (each with their heads protruding from sealed openings in the outer wall), with sufficient space inside for a nurse or a respiratory therapist to be inside the sealed room, attending the patients.[2]

Smaller, single-patient versions of the iron lung include the so-called cuirass ventilator (named for the cuirass, a torso-covering body armor). The cuirass ventilator encloses only the patient's torso, or chest and abdomen, but otherwise operates essentially the same as the original, full-sized iron lung. A lightweight variation on the cuirass ventilator is the jacket ventilator or poncho or raincoat ventilator, which uses a flexible, impermeable material (such as plastic or rubber) stretched over a metal or plastic frame over the patient's torso.[1][7][13][14]

Method and use

An iron lung ward, as mocked-up for a film, circa 1953

Humans, like most mammals, breathe by negative pressure breathing:[15] the rib cage expands and the diaphragm contracts, expanding the chest cavity. This causes the pressure in the chest cavity to decrease, and the lungs expand to fill the space. This, in turn, causes the pressure of the air inside the lungs to decrease (it becomes negative, relative to the atmosphere), and air flows into the lungs from the atmosphere: inhalation. When the diaphragm relaxes, the reverse happens and the person exhales. If a person loses part or all of the ability to control the muscles involved, breathing becomes difficult or impossible.

Invention and early use

Initial development

Iron lung from the 1950s in the Gütersloh Town Museum. In Germany, fewer than a dozen of these breathing machines are available to the public.

In 1670, English scientist John Mayow came up with the idea of external negative pressure ventilation. Mayow built a model consisting of bellows and a bladder to pull in and expel air.[16] The first negative pressure ventilator was described by British physician John Dalziel in 1832. Successful use of similar devices was described a few years later. Early prototypes included a hand-operated bellows-driven "Spirophore" designed by Dr Woillez of Paris (1876),[17] and an airtight wooden box designed specifically for the treatment of polio by Dr Stueart of South Africa (1918). Stueart's box was sealed at the waist and shoulders with clay and powered by motor-driven bellows.[18]

Drinker and Shaw tank

A Drinker iron lung displayed at the chapel of Netley Hospital, 2018

The first of these devices to be widely used however was developed in 1928 by Phillip Drinker and Louis Shaw of the United States.[19] The iron lung, often referred to in the early days as the "Drinker respirator", was invented by Philip Drinker (1894–1972) and Louis Agassiz Shaw Jr., professors of industrial hygiene at the Harvard School of Public Health.[20][21][22][23] The machine was powered by an electric motor with air pumps from two vacuum cleaners. The air pumps changed the pressure inside a rectangular, airtight metal box, pulling air in and out of the lungs.[24] The first clinical use of the Drinker respirator on a human was on October 12, 1928, at the Boston Children's Hospital in the US.[21][25] The subject was an eight-year-old girl who was nearly dead as a result of respiratory failure due to polio.[23] Her dramatic recovery within less than a minute of being placed in the chamber helped popularize the new device.[22]

Variations

Boston manufacturer Warren E. Collins began production of the iron lung that year.[26][27] Although it was initially developed for the treatment of victims of coal gas poisoning, it was most famously used in the mid-20th century for the treatment of respiratory failure caused by polio.[20]

Danish physiologist August Krogh, upon returning to Copenhagen in 1931 from a visit to New York where he saw the Drinker machine in use, constructed the first Danish respirator designed for clinical purposes. Krogh's device differed from Drinker's in that its motor was powered by water from the city pipelines. Krogh also made an infant respirator version.[28]

In 1931, John Haven Emerson (1906–1997) introduced an improved and less expensive iron lung.[29][30] The Emerson iron lung had a bed that could slide in and out of the cylinder as needed, and the tank had portal windows which allowed attendants to reach in and adjust limbs, sheets, or hot packs.[24] Drinker and Harvard University sued Emerson, claiming he had infringed on patent rights. Emerson defended himself by making the case that such lifesaving devices should be freely available to all.[24] Emerson also demonstrated that every aspect of Drinker's patents had been published or used by others at earlier times. Since an invention must be novel to be patentable, prior publication/use of the invention meant it was not novel and therefore unpatentable. Emerson won the case, and Drinker's patents were declared invalid.

The United Kingdom's first iron lung was designed in 1934 by Robert Henderson, an Aberdeen doctor. Henderson had seen a demonstration of the Drinker respirator in the early 1930s and built a device of his own upon his return to Scotland. Four weeks after its construction, the Henderson respirator was used to save the life of a 10-year-old boy from New Deer, Aberdeenshire who had poliomyelitis. Despite this success, Henderson was reprimanded for secretly using hospital facilities to build the machine.[31][32]

Both respirator

A Both cabinet respirator being used to treat a patient at the 110th Australian Military Hospital in 1943

The Both respirator, a negative pressure ventilator, was invented in 1937 when Australia's epidemic of poliomyelitis created an immediate need for more ventilating machines to compensate for respiratory paralysis. Although the Drinker model was effective and saved lives, its widespread use was hindered by the fact that the machines were very large, heavy (about 750 lbs or 340 kg), bulky, and expensive. In the US, an adult machine cost about $2,000 in 1930, and £2,000 delivered to Melbourne in 1936. The cost in Europe in the mid-1950s was around £1,500. Consequently, there were few of the Drinker devices in Australia and Europe.[33]

The South Australia Health Department asked Adelaide brothers Edward and Don Both to create an inexpensive "iron lung".[34] Biomedical engineer Edward Both designed and developed a cabinet respirator made of plywood that worked similarly to the Drinker device, with the addition of a bi-valved design which allowed temporary access to the patient's body.[33] Far cheaper to make (only £100) than the Drinker machine, the Both Respirator also weighed less and could be constructed and transported more quickly.[33][35] Such was the demand for the machines that they were often used by patients within an hour of production.[36]

Both-Nuffield iron lung display at the Thackray Medical Museum, Leeds. Pictures show assembly at the Morris motor works

Visiting London in 1938 during another polio epidemic, Both produced additional respirators there which attracted the attention of William Morris (Lord Nuffield), a British motor manufacturer and philanthropist. Nuffield, intrigued by the design, financed the production of approximately 1700 machines at his car factory in Cowley and donated them to hospitals throughout all parts of Britain and the British Empire.[36] Soon, the Both-Nuffield respirators were able to be produced by the thousand at about one-thirteenth the cost of the American design.[34] By the early 1950s, there were over 700 Both-Nuffield iron lungs in the United Kingdom, but only 50 Drinker devices.[37]

Polio epidemic

Staff in a Rhode Island hospital examine a patient in an iron lung tank respirator during a polio epidemic in Rhode Island in 1960. The iron lung encased the thoracic cavity in an air-tight chamber used to create negative pressure around the thoracic cavity, thereby causing air to enter the lungs to equalize intrapulmonary pressure.

Rows of iron lungs filled hospital wards at the height of the polio outbreaks of the 1940s and 1950s, helping children, and some adults, with bulbar polio and bulbospinal polio. A polio patient with a paralyzed diaphragm would typically spend two weeks inside an iron lung while recovering.[38][39]

Modern development and usage

Polio vaccination programs have virtually eradicated new cases of poliomyelitis in the developed world. Because of this, the development of modern ventilators, and widespread use of tracheal intubation and tracheotomy, the iron lung has mostly disappeared from modern medicine. In 1959, 1,200 people were using tank respirators in the United States, but by 2004 that number had decreased to just 39.[38] By 2014, only 10 people were left with an iron lung.[40]

Replacement

Positive pressure ventilation systems are now more common than negative pressure systems. Positive pressure ventilators work by blowing air into the patient's lungs via intubation through the airway; they were used for the first time in Blegdams Hospital, Copenhagen, Denmark, during a polio outbreak in 1952.[1][41][42] It proved a success and soon superseded the iron lung throughout Europe.

The iron lung now has a marginal place in modern respiratory therapy. Most patients with paralysis of the breathing muscles use modern mechanical ventilators that push air into the airway with positive pressure. These are generally efficacious and have the advantage of not restricting patients' movements or caregivers' ability to examine the patients as significantly as an iron lung does.

Continued use

Despite the advantages of positive ventilation systems, negative pressure ventilation is a truer approximation of normal physiological breathing and results in a more normal distribution of air in the lungs. It may also be preferable in certain rare conditions,[1] such as central hypoventilation syndrome, in which failure of the medullary respiratory centers at the base of the brain results in patients having no autonomic control of breathing. At least one reported polio patient, Dianne Odell, had a spinal deformity that caused the use of mechanical ventilators to be contraindicated.[43]

At least a few patients today still use the older machines, often in their homes, despite the occasional difficulty of finding replacement parts.[44]

Joan Headley of Post-Polio Health International said that as of May 28, 2008, about 30 patients in the U.S. were still using an iron lung.[45] That figure may be inaccurately low; Houston alone had 19 iron lung patients living at home in 2008.[46]

Martha Mason of Lattimore, North Carolina died on May 4, 2009, after spending 61 of her 72 years in an iron lung.[47]

On October 30, 2009, June Middleton of Melbourne, Australia, who had been entered in the Guinness Book of Records as the person who spent the longest time in an iron lung, died aged 83, having spent more than 60 years in her iron lung.[48]

In 2013, the Post-Polio Health International (PHI) organizations estimated that only six to eight iron lung users were in the United States; as of 2017, its executive director knew of none. Press reports then emerged, however, of at least three (perhaps the last three)[49] users of such devices,[50] sparking interest amongst those in the makerspace community such as Naomi Wu[51] in the manufacture of the obsolete components, particularly the gaskets.[52][53] One is retired lawyer Paul Alexander, 77, of Dallas.[54]

In 2021, the National Public Radio programs Radio Diaries and All Things Considered gave a report on Martha Lillard, one of the last two Americans depending on the daily use of an iron lung, which she had been using since 1953. In her audio interview, she reported that she was having problems obtaining replacement parts to keep her machine working properly.[55]

COVID-19 pandemic

In early 2020, reacting to the COVID-19 pandemic, to address the urgent global shortage of modern ventilators (needed for patients with advanced, severe COVID-19), some enterprises developed prototypes of new, readily-producible versions of the iron lung. These developments included:

See also

References

  1. 1 2 3 4 5 6 7 Shneerson, Dr. John M., Newmarket General Hospital, (Newmarket, Suffolk, U.K.), "Non-invasive and domiciliary ventilation: negative pressure techniques," #5 of series "Assisted ventilation" in Thorax, 1991;46:131–35, retrieved April 12, 2020
  2. 1 2 3 4 5 Rockoff, Mark, M.D., "The Iron Lung and Polio,", video (8 minutes), January 11, 2016, OPENPediatrics and Boston Children's Hospital on YouTube, retrieved April 11, 2020 (historical background and images, explanatory diagrams, and live demonstrations)
  3. 1 2 3 Jackson, Christopher D., MD, Dept. of Internal Medicine, and Muthiah P Muthiah, MD, FCCP, D-ABSM, Assoc. Prof. of Medicine, Div. of Pulmonary / Critical Care / Sleep Medicine, Univ. of Tennessee College of Medicine-Memphis, et.al., "What is the background of the iron lung form of mechanical ventilation?," April 11, 2019, Medscape, retrieved April 12, 2020 (short summary of iron history and technology, with photo)
  4. ↑ Grum, Cyril M., MD, and Melvin L. Morganroth, MD, "Initiating Mechanical Ventilation," in Intensive Care Medicine 1988;3:6–20, retrieved April 12, 2020
  5. ↑ Corrado, A.; Ginanni, R.; Villella, G.; Gorini, M.; Augustynen, A.; Tozzi, D.; Peris, A.; Grifoni, S.; Messori, A.; Nozzoli, C.; Berni, G. (March 2004). "Iron lung versus conventional mechanical ventilation in acute exacerbation of COPD". The European Respiratory Journal. 23 (3): 419–24. doi:10.1183/09031936.04.00029304. ISSN 0903-1936. PMID 15065832.
  6. ↑ Buncombe, Andrew (November 22, 2017). "America's last iron lung users on their lives spent inside obsolete ventilators". The Independent.
  7. 1 2 3 "Modern iron lung designed to address ventilator shortage,", April 6, 2020, New Atlas, retrieved April 11, 2020
  8. ↑ Laderas, Crystal, reporter: "Alberta team building modern 'iron lung' for COVID-19 in dire environments,", (video & text), March 25, 2020, as updated March 26, 2020, City News / Citytv, Edmonton, Alberta, Canada – also broadcast as "Bioengineers build modern 'iron lung' for COVID-19 in dire environments: Scientists build a prototype 'iron lung' for COVID-19 patients in crisis environments. The machine is a last resort for patients when hospital ventilators are not available," (video only), March 25, 2020, 660 News / CityNews / Citytv, Calgary, Alberta, Canada, retrieved April 23, 2020
  9. 1 2 "One Kansas company is switching gears to make iron lung ventilators," (video & text), April 10, 2020, KSNW-TV, retrieved April 11, 2020
  10. 1 2 Allen, Margaret, "Hess offers iron lung for COVID-19," Archived February 25, 2021, at the Wayback Machine April 9, 2020, Hays Daily News, retrieved April 11, 2020
  11. 1 2 "The Iron Lung," Science Museum Group, Kensington, London, England, (illustrated description of the device and its history), retrieved April 11, 2020
  12. 1 2 "How Does Iron Lung Work?: Polio Survivor, 82, Among Last to Use Breathing Equipment," August 21, 2018, Newsweek retrieved April 11, 2020
  13. ↑ "The 'iron lung' and the modern 'ventilation'," Oxy.gen, retrieved April 11, 2020
  14. ↑ "Poncho," by medical device manufacturer Dima Italia Srl of Bologna, Italy (picture of jacket ventilator ("poncho"), and other information.), retrieved April 12, 2020
  15. ↑ "Gas Exchange in Humans". Archived from the original on April 23, 2009. Retrieved July 1, 2011.
  16. ↑ Schlager, Neil (2000). Science and Its Times: Understanding the Social Significance of Scientific Discovery, Vol. 6: 1900–1950. Farmington Hills, Michigan: Gale. p. 348. ISBN 978-0787639389.
  17. ↑ Emerson, John H (July 1998). "Some Reflections on Iron Lungs and Other Inventions" (PDF). Respiratory Care. 43 (7): 577. Archived from the original on March 24, 2006. Retrieved October 12, 2016.{{cite journal}}: CS1 maint: bot: original URL status unknown (link)
  18. ↑ Gould, Tony (1997). A Summer Plague: Polio and Its Survivors. New Haven: Yale University Press. p. 90. ISBN 978-0300072761.
  19. ↑ Laurie, Gini (2002). "Ventilator users, home care, and independent living: a historical perspective". In Gilgoff, Irene S. (ed.). Breath of Life: The Role of the Ventilator in Managing Life-Threatening Illnesses. Lanham, Maryland: Scarecrow Press, Inc. pp. 161–201. ISBN 978-0-8108-3488-0.
  20. 1 2 Sherwood, RJ (1973). "Obituaries: Philip Drinker 1894–1972". The Annals of Occupational Hygiene. 16 (1): 93–94. doi:10.1093/annhyg/16.1.93.
  21. 1 2 Gorham, J (1979). "A medical triumph: the iron lung". Respiratory Therapy. 9 (1): 71–73. PMID 10297356.
  22. 1 2 "2010-2011 Student Handbook" (PDF). Cambridge, Massachusetts: The Harvard Education and Research Center for Occupational Safety and Health. 2010. Archived from the original (PDF) on January 2, 2011. Retrieved July 2, 2011.
  23. 1 2 P.C. Rossin College of Engineering and Applied Science (2011). "Philip Drinker '17". Distinguished Alumni: Great Talents & Bright Minds. Bethlehem, Pennsylvania: Lehigh University. Archived from the original on June 15, 2011. Retrieved July 1, 2011.
  24. 1 2 3 Kenneth E. Behring Center (2011). "The iron lung and other equipment". Whatever happened to polio?. Washington, DC: National Museum of American History. Archived from the original on June 4, 2011. Retrieved July 2, 2011.
  25. ↑ "Today in History: Iron Lung Used for the First Time (1928)". Tebyan.net. Retrieved November 14, 2013.
  26. ↑ Julie K. Silver; Daniel J. Wilson (2007). Polio Voices. Santa Barbara: Praeger Publishers. p. 141. ISBN 9780275994921.
  27. ↑ "Artificial Lung on Wheels Prove Life Saver" Popular Mechanics, December 1930 photo of earliest production units from Boston
  28. ↑ Kirby, Richard R. (1985). Mechanical Ventilation. New York: Churchill Livingstone. p. 9. ISBN 978-0443080630.
  29. ↑ Geddes, LA (2007). "The history of artificial respiration". IEEE Engineering in Medicine and Biology Magazine. 26 (6): 38–41. doi:10.1109/EMB.2007.907081. PMID 18189086. S2CID 24784291.
  30. ↑ "Iron Lung". National Museum of American History. Retrieved July 1, 2011.
  31. ↑ Wills, Elspeth (2002). Scottish Firsts: A Celebration of Innovation and Achievement. Edinburgh: Mainstream Publishing. pp. 51–52. ISBN 978-1840186116.
  32. ↑ Thomas, Campbell (February 15, 2000). "Dr Robert Henderson". The Herald. Retrieved March 10, 2013.
  33. 1 2 3 Trubuhovich, Ronald V. (2006). "Notable Australian contributions to the management of ventilatory failure of acute poliomyelitis". Critical Care and Resuscitation. 8 (4): 383–85. PMID 17227281.
  34. 1 2 Healey, John (1998). "The Both Brothers and the 'Iron Lung'". South Australian Medical Heritage Society Inc. Retrieved March 10, 2013.
  35. ↑ "Memories of polio and those who wrestled with it". The Sydney Morning Herald. December 7, 2004. Retrieved March 10, 2013.
  36. 1 2 Langmore, Diane, ed. (2009). Australian Dictionary of Biography: Volume 17 1981–1990 A–K. Carlton, Victoria: Melbourne University Publishing. p. 129. ISBN 978-0522853827.
  37. ↑ Lawrence, Ghislaine (February 23, 2002). "The Smith-Clarke Respirator". The Lancet. 359 (9307): 716. doi:10.1016/s0140-6736(02)07819-4. PMID 11879908. S2CID 54283110.
  38. 1 2 "NMAH | Polio: The Iron Lung and Other Equipment". National Museum of American History. Smithsonian Institution. Retrieved March 28, 2020.
  39. ↑ Resnick, Brian (January 10, 2012). "What America Looked Like: Polio Children Paralyzed in Iron Lungs". The Atlantic.
  40. ↑ Conlon, Shelly (August 24, 2014). "North Texan one of 10 still living in iron lung". The Washington Times. Associated Press. Retrieved March 28, 2020.
  41. ↑ Louise Reisner-Sénélar (2009). "The Danish anaesthesiologist Björn Ibsen a pioneer of long-term ventilation on the upper airways". Retrieved July 1, 2011.
  42. ↑ Wackers, Ger (1994). "Chapter 4". Theaters of truth and competence. Intermittent positive pressure respiration during the 1952 polio-epidemic in Copenhagen. Archived from the original on December 23, 2007. Retrieved July 1, 2011.
  43. ↑ "Power failure kills iron lung lady". The Sydney Morning Herald. May 29, 2008. Retrieved July 1, 2011.
  44. ↑ "60 years in an iron lung: US polio survivor worries about new global threat". NBC News. November 30, 2013.
  45. ↑ "Woman dies after life spent in iron lung". May 28, 2008. Archived from the original on October 22, 2008. Retrieved July 1, 2011.
  46. ↑ Lauran Neergaard (January 13, 2009). "Emergency officials struggle to find those on life-support during power outages". Retrieved January 1, 2014.
  47. ↑ Fox, Margalit (May 10, 2009). "Martha Mason, Who Wrote Book About Her Decades in an Iron Lung, Dies at 71". The New York Times. Retrieved July 1, 2011.
  48. ↑ "Dead after 60 years in iron lung". The Sydney Morning Herald. November 1, 2009. Retrieved July 1, 2011.
  49. ↑ Mazziotta, Julie (August 21, 2018). "Polio Survivor, 82, Is One of the Last 3 People in the U.S. to Use an Iron Lung". People Magazine.
  50. ↑ Brown, Jennings (November 20, 2017). "The Last of the Iron Lungs". Gizmodo. Retrieved November 25, 2017.
  51. ↑ Lewin, Day (November 25, 2017). "A Callout: Parts for an Iron Lung". Hackaday. Retrieved November 25, 2017.
  52. ↑ Naomi Wu [@reaksexycyborg] (November 23, 2017). "Via @NireBryce – we've got a nice old lady running out of collars for her iron lung. Lot of 💩 going on in the world we can't do anything about – but this seems 100% doable. @hackaday, @make, textile tech folks – any ideas? From https://gizmodo.com/the-last-of-the-iron-lungs-1819079169 …" (Tweet) – via Twitter.
  53. ↑ Kobie, Nicole (November 28, 2017). "A woman on an iron lung is running out of the spare parts she needs to live. Cue the maker community..." Wired.
  54. ↑ "Living inside a canister: this polio survivor is one of few people left using iron lung". Stuff (Fairfax). June 1, 2018.
  55. ↑ Kelly, Erin; Escarce, Alissa (October 25, 2021). "Decades after polio, Martha is among the last to still rely on an iron lung to breathe (includes audio interview)". All Things Considered. National Public Radio. (Written transcript of audio episode).
  56. ↑ "Exovent iron lung concept offers alternative to Covid-19 ventilators". The Engineer. April 2, 2020.

Further reading

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  1. ↑ "Excerpt from Cat's Eye". Penguin Random House Canada. Retrieved October 12, 2023.
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