Thymidine triphosphate
Skeletal formula of thymidine triphosphate, 3- negative charge
Space-filling model of the thymidine triphosphate molecule, 4- negative charge
Names
IUPAC name
Thymidine 5′-(tetrahydrogen triphosphate)
Systematic IUPAC name
O1-{[(2R,3S,5R)-5-(2,4-Dioxo-5-methyl-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxyoxolan-2-yl]methyl} tetrahydrogen triphosphate
Other names
dTTP, 2′-Deoxythymidine triphosphate
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.006.064
MeSH thymidine+5'-triphosphate
UNII
  • CC1=CN(C(=O)NC1=O)C2CC(C(O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O
Properties
C10H17N2O14P3
Molar mass 482.168
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Thymidine triphosphate (TTP), also called deoxythymidine triphosphate (dTTP),[1] is one of the four nucleoside triphosphates that are used in the in vivo synthesis of DNA. Unlike the other deoxyribonucleoside triphosphates, thymidine triphosphate does not always contain the "deoxy" prefix in its name.[2] The corresponding ribonucleoside triphosphate is called uridine triphosphate.

It can be used by DNA ligase to create overlapping "sticky ends" so that protruding ends of opened microbial plasmids may be closed up.

References

  1. ↑ "Thymidine 5'-triphosphate (PAMDB000346)". University of Maryland, Baltimore. 2018-01-22. Archived from the original on 2023-10-29. Retrieved 2023-10-29.
  2. ↑ Coghill, Anne M.; Garson, Lorrin R., eds. (2006). The ACS style guide: effective communication of scientific information (3rd ed.). Washington, D.C.: American Chemical Society. p. 244. ISBN 978-0-8412-3999-9.


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