DMSO is dimethyl sulfoxide, an organosulfur compound with the formula (CH3)2SO.
DMSO may also refer to:
- Deuterated DMSO, an isotopologue of dimethyl sulfoxide used as a solvent in Nuclear Magnetic Resonance spectroscopy.
- Defense Modeling and Simulation Office, the former name of the Modeling and Simulation Coordination Office in the U.S. Department of Defense
- Des Moines Symphony Orchestra, in Des Moines, Iowa, United States
- Driving Motor Standard Open, a type of rail vehicle found in British multiple unit trains such as the British Rail Class 315
- "D.M.S.O.", a song by Dead Kennedys from the album Bedtime For Democracy
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