Dr Rusty Venture

Dr Thaddeus "Rusty" Venture (voiced by James Urbaniak): Dean and Hank's father, head of Venture Industries, and clone-brother of The Monarch. He is a capable scientist and inventor, but his greed, lack of formal education, and insistence on cutting corners result in his attempts at technological innovation failing, resulting in chaos for him, his family, friends, and sometimes the world at large. Although the money he earns is enough to support him and his family, it's also not enough to satisfy his greed and his ambitions to be as wealthy and successful as his father. While he cares for his sons, his father's abusive and negligent parenting influences the way he treats them, sometimes being as indifferent to them as his father was to him. It is revealed in season 7 that Dr Venture is not the original, but rather a clone of the first Rusty Venture, who died in the past.

Brock Samson

Brock Fitzgerald Samson (voiced by Patrick Warburton): Born in Omaha, Nebraska to a single mother. A one-half Swedish, one-quarter Polish, one-quarter Winnebago "murder machine" who acts as a bodyguard to the Venture family and attended the same university as Dr Venture until he was kicked out for accidentally killing one of his football team's teammates. Although Brock possesses a license to kill, he refuses to use a gun and instead wields a Ka-Bar fighting knife as his signature weapon. He has shown signs of being conflicted with his place in the world and unsure about his purpose, and has a personal code of ethics regarding innocents and whom he will kill if they are a threat to him and or the Ventures. He owns an orange 1969 Dodge Hemi Charger named "Adrianne", which he is often seen driving or washing shirtless at the Venture compound. H.E.L.P.eR.'s head was briefly embedded in his chest following the car Henchman 24 was in exploding, which also resulted in 24's death; the head was later removed and replaced with a metal plate.

Hank Venture

Henry Allen "Hank" Venture (voiced by Christopher McCulloch): A teenage boy, one half of the eponymous pair, the older fraternal twin with blond hair. He is shown as the more outgoing and daring of the pair and is more attracted to action and adventure, seeing himself as a vigilante superhero. In season 4, he became even more rebellious when Brock left, even losing his virginity to an older woman who turns out to be the mother of his best friend. After briefly joining the former Henchman 21's version of S.P.H.I.N.X., Hank attained the power suit of former S.P.H.I.N.X. member The Countess, which he wore until it was stolen and destroyed, leaving Hank in physical therapy for some time because of his atrophied muscles. In season 6, Hank foregoes college and gets a job at a pizzeria as a delivery boy. He also begins a relationship with Sirena Ong, the daughter of his father's current Guild-assigned villain, Wide Wale. In season 7, he falls into a coma after he discovers Sirena cheating on him with Dean, but recovers.

Dean Venture

Dean Venture (voiced by Michael Sinterniklaas): A teenage boy, one half of the eponymous pair, the younger fraternal twin with red hair. While more timid than Hank, he shows signs of being more emotionally mature than his brother. Dean is more favoured and liked than Hank by their father who grooms Dean to succeed him as the heir to Venture Industries. Like his brother, Dean has been killed over a dozen times, but each time he is replaced with an exact clone who has no memory of the death. After being dumped by Triana and discovering he is a clone, Dean becomes more of an emo, dressing in a black "speedsuit", moving out of his childhood bedroom, and becoming more unwilling to go with his family on adventures. However, Hank snaps him out of it by showing optimism and being a part of their family. In season 6, Dean attends the fictional Stuyvestant University in New York, where he thrives as a student of philosophy, and finds a friend with Brown Widow, his roommate. In season 7, he has an affair with Hank's girlfriend, Sirena Ong, but regrets doing so.

H.E.L.P.eR.

H.E.L.P.eR. (voiced by Christopher McCulloch; credited as "Soul-Bot"): An acronym for Humanoid Electronic Lab Partner Robot. The Venture family's helper robot communicates via electronic beeps. Though he is very sensitive, the Ventures often treat him like an old appliance or pet. The robot routinely gets smashed to pieces during their adventures, but seems to get repaired by the next show.

Sergeant Hatred

Sergeant Hatred AKA Courtney Robert Haine^[1] (voiced by Brendon Small in season 2 and Christopher McCulloch from season 3 onward): Brock's former supervisor in the O.S.I., husband of Native American villainess Princess Tinyfeet, and the Venture family's bodyguard. He is a large muscular man with a giant red 'H' tattooed on his face and wears military fatigues. Despite being a convicted child molester for having slept with a 17-year-old, he is liked and respected throughout the supervillain community for his unfailing politeness and generosity; certain episodes also reveal that he knows his sexual attraction to teenagers is wrong, and tries to keep it in check using medication and electroshock therapy. He is known for his caring nature behind his battle-hardened exterior.

Dermott Fictel

Dermott Fictel (voiced by Doc Hammer): An obnoxious teenager who first appears in "The Buddy System"; he was hinted to be the son of Brock Samson. Dermott is a compulsive liar and frequently interjects wild, and often clearly false, claims about his abilities and past deeds into unrelated conversations. He is Hank's best friend and occasionally visits the Venture compound from the nearby trailer park where he and his "mother" live. In "Everybody Comes to Hank's" Hank sleeps with Nikki Fictel (voiced by Kate McKinnon) whom Dermott knows as his older sister, but is actually his mother. His real father is also revealed to be Rusty, making him Hank and Dean's half-brother. He stays behind when the Venture family moves to New York and later joins the OSI, being accepted as an operative despite his lack of training, thanks to a good word put in for him by Dr Venture.

Dr Jonas Venture Jr.

Dr Jonas Venture Jr., also known as J.J. (voiced by James Urbaniak): Dr Venture's deformed twin, who was absorbed by Rusty in the womb and surgically freed from Rusty's body after being mistaken for a tumour. Although he has the body of an infant, he has an adult appearance and seems to have inherited his father's brilliance. He is scientifically astute, hard-working, attractive to women, and a multi-billionaire CEO of a profitable corporation. However, his worship of his father causes the original Team Venture to dislike him greatly, as he ignores their importance to his father's life, business, and legacy. JJ dies in "All This and Gargantua-2" when he sacrifices himself to prevent his space station, Gargantua-2, from harming people, when it self-destructs due to sabotage from The Investors. In his will, he bequeaths his fortune, the New York City Headquarters, and technology patents to his brother.

Triana Orpheus

Triana Orpheus (voiced by Lisa Hammer): Dr Orpheus's 17-year-old quasi-goth daughter. She has purple hair and is fairly friendly with the Venture twins. She and Dean become close until they have a major fight and fall out after she chooses to date another boy called Raven over Dean. In season four, it is revealed that she has inherited her father's abilities when she encounters her father's mystical mentor who purposely took up residence in her closet because of her power.

Pete White

Pete White (voiced by Christopher McCulloch): An albino computer scientist and co-founder of Conjectural Technologies. He went to college with Venture, Samson, Baron Ünderbheit, and The Monarch, where he hosted a new wave radio show called "The White Room". After graduating with a doctorate in computer science, White and Billy Quizboy worked in tandem on a Jeopardy-style game show, called "QuizBoys", in which Pete hosted and Billy took part. After being caught cheating and rigging the shows in their favour, White and Quizboy were fired and left to find new lives. While the two had a short falling out, Pete eventually rejoined Billy. They found refuge in a trailer near the Venture Compound. Like Venture and Quizboy, White is lazy and half-hearted in his efforts, despite being very well-skilled and knowledgeable in super science and technology. In season six, after Dr Venture inherits his brother's company and fortune, he and Billy move to New York City with the Venture family and become one of Dr Venture's leading scientists, helping him invent breakthrough technology to sell through Ventech.

Billy Quizboy

William Whalen, a.k.a. Master Billy Quizboy (voiced by Doc Hammer): Self-proclaimed "boy genius" Billy Whalen is an adult with a speech impediment and growth hormone deficiency. He suffers from hydrocephalus, although his intellect seems to be unaffected by this condition. He starred as a contestant on the game show Quizboys hosted by Pete White. When White cheated for him, they were both kicked off the show and Billy's winnings were frozen by the SEC. White and Billy approached Dr Venture, looking to work for him, but Rusty turned them both away. After this, White accidentally entered Billy into a dogfight. Thinking it was an underground quiz match, Billy lost a hand and eye in the mix-up. Billy left White and was recruited by Brock Samson and Hunter Gathers, who provided him with a mechanical hand and camera eye. Brock and Hunter sent Billy undercover to spy on Professor Hamilton Fantomas and dig up dirt on the possible existence of the Guild of Calamitous Intent. Fantomas had Billy's help with his experiment, but the experiment went wrong. Fantomas became Phantom Limb and Billy lost his left eye again. After a mind wipe, Brock smuggled Billy out of O.S.I. and left him with White. Despite not having a formal education and training, he became a medical doctor, neurogeneticist and co-founder of Conjectural Technologies. He also briefly joined the Order of the Triad in exchange for his performing brain surgery on the Outrider after claiming he should be paid for his endeavour. In season 5, Billy's old nemesis Augustus St. Cloud became his and White's designated arch-enemy, much to the duo's delight. In Season 6, he and Peter move with The Venture family to New York City to assist Dr Venture with inventing breakthrough technology to sell under the Ventech brand.

The Pirate Captain

The Pirate Captain (voiced by Christopher McCulloch): The leader of the "ghost pirates" in "Ghosts of the Sargasso". After his initial encounter with the Venture family, he began living on the X-2 after having difficulties in finding a job. When Jonas Jr. acquired the ship, he hired the captain. He has not been referred to by any name or nickname other than "The Captain" so far. He resided with Jonas Jr. on Spider Skull Island and fulfilled the duties of a butler, caretaker, and right-hand man. The Captain always refers to Jonas as "Chairman". Later, after J.J.'s death, the Captain becomes an employee of Dr. Venture when he inherits J.J.'s business in New York City.

The Order of the Triad

Original Team Venture

• Dr. Jonas Venture Sr. (voiced by Paul Boocock): Deceased father of Dr. Rusty Venture, Jonas Junior, and as of season 7, it is revealed that he is also The Monarch's father. He was the foremost super scientist and adventurer in the world of his time. He created what is now known as Venture Industries and led the original Team Venture. While his public reputation was of a brilliant scientist, adventurer, and superhero, in reality, Jonas was a manipulative, sociopathic womanizer of questionable morals and ethics and was considered by the Guild to have been a greater villain than any of those he fought. He seemed to have considered Rusty as an unplanned and unwanted birth, and as a result, he generally ignored his son's existence in favor of drinking, partying, and sex. When he did pay attention to Rusty, he also subjected him to years of emotional manipulation and abuse. Season 7 revealed his most egregious act that would define the history of the entire series. He blackmailed his best friend Blue Morpho with a sex tape of him cheating on his wife into doing his dirty work for him, forcing Morpho's sidekick, Kano, into Team Venture, and impregnating Morpho's wife under the guise of "assisting" with their infertility issues. Morpho's wife has a baby through Jonas who would later grow up to be The Monarch. When the Morpho was killed in a plane crash, Jonas transferred his brain into a robot body and called him Venturion, an act that disgusted and horrified the original Team Venture. When Venturion malfunctioned and attacked Rusty Venture, Kano fatally disabled it, and Jonas disposed of its remains. Venturion's body was captured by Dr. Zinn and the Guild of Calamitous Intent who reprogrammed him into a villain called "Vendata." He later confronts and kills Jonas by ejecting him into space. Team Venture recovered his remains and embedded them in the ProBLEM device on the station which kept him in stasis until he could be saved. The ProBLEM was found by his son, JJ years later after the Gargantua-1 crashed on Earth. Unaware of what was inside it, he placed it in the lobby of Ventech headquarters as an art piece but was wired into the security and technology of the building. His brain, however, was still alive and thus used the connection to the building's security and technology to upload his consciousness to haunt Dr. Venture and his family. Through the building's wi-fi, he reveals to his son Rusty and the original Team Venture his real purpose for Venturion/Vendata: to transfer his consciousness into Vendata's brain and using the robot as a temporary vessel until Rusty cloned him a new body. This plan was foiled by Vendata/Blue Morpho who destroys the ProBLEM machine in a fight with Jonas in virtual reality, presumably killing them both.
• The Action Man, whose real name is Rodney (voiced by Christopher McCulloch): A retired American supersoldier with flatulence problems and "plastic knees" that hinder his movements. He married Major Tom's widow, Jeannie, after Tom's tragic accident. Like Jonas, he wasn't well trained with children and was hinted to have had some bad moments with young Rusty. He had a habit of waking up Rusty Venture back in the old days by placing an unloaded gun against the sleeping boy's head and pulling the trigger, then saying, "Not today, Rusty". According to Rose, Rodney was a womanizer and a junkie, both of which he denied, claiming it was all in the past and never cheated on Jeanie, which is most likely a lie. "Action Man" is also the name of Hasbro's original 12 Inch GI Joe figures, released outside the United States. The Action Man moved to a retirement community in Boca Raton, Florida, where he is alone following the death of Jeannie. He briefly had Dr. Entmann as a roommate, only to accidentally crush him with his rocking chair while Dr. Entmann was in a shrunken-down state. He later dates fellow retired superhero, and Billy Quizboy's mother, Rose and moves in with Colonel Gentleman.
• Colonel Horace Gentleman (voiced by Christopher McCulloch impersonating Sean Connery): Retired member of the original Team Venture and later ersatz leader of the reformed Team Venture. He is a Scottish gentleman and adventurer in the vein of Allan Quatermain and James Bond. The influence is apparent in the similarity of his voice to that of Sean Connery, who has played both characters in movies. He dresses in an old-fashioned British suit, complete with cane and fedora. It is briefly implied that he is a pederast and this was later confirmed by the creators.^[2] In the second season, Hank and Dean find him apparently dead of unspecified causes; however, it is revealed in "Now Museum-Now You Don't" that he was merely in a diabetic coma and is still alive. He is an ethnic/gender chauvinist, and has a penchant for writing out random lists in his notebook. He briefly bears a grudge against Rusty Venture for breaking the heart of his stepdaughter, Dr. Quymn, whom he has retained some affection for. Col. Gentleman lives in Tangier, it formerly being a haven for the world's elite and greatest intellectuals, but in recent years he has realized that he is the only one left, and is dejected that Kiki has broken up with him for the last time. At the end of season 5, he realizes that there is no reason for him to stay in Tangier anymore and moves back to the United States, becoming the Action Man's new roommate.
• Kano (voiced by Christopher McCulloch): Retired member of the original Team Venture. He is a master of the martial arts and an accomplished pilot and was likely inspired by the Green Hornet's assistant Kato. In earlier episodes, he never speaks and only communicates by way of origami and sparse gestures; however this is attributed to a vow of silence he'd taken as revealed in the episode "ORB". The vow was made when he took a great man from the world, which Brock believed was Jonas Venture Sr. As Col. Gentleman described him, his hands are "powerful enough to crush a boulder, yet delicate enough to crush a butterfly." Although not a villain, his silent demeanor, fighting skills and brute strength all correspond with the bodyguard/henchman archetype found in many works of fiction, with particular similarities to Oddjob. In addition to his skill in fighting and origami, Kano also appears to be a capable aircraft pilot. Kano has also displayed an ability to breathe fire in the episode "Now Museum-Now You Don't". On the DVD commentary, it is revealed that this is where his name originates in that it is short for "Volcano". Season 7 revealed that Kano was originally the bodyguard of the Blue Morpho, The Monarch's father. Kano was forced into the original Team Venture away from the Blue Morpho after Jonas had blackmailed Morpho. When Jonas resurrected the Blue Morpho as the cyborg Venturion after his death in a plane crash, Venturion malfunctioned and attacked Rusty, forcing Kano to snap his neck. According to the other members of the original team, Kano never spoke again after this event, thus "the great man" whom Kano killed before taking his vow of silence.
• Otto Aquarius (voiced by T. Ryder Smith): Retired member of the original Team Venture. An exiled son of Atlantis, he is half-human and half-Atlantean, which grants him a greatly extended life-span and the power to communicate telepathically with sea creatures. Most recently, he has converted to either the Church of Jesus Christ of Latter-day Saints (according to the special features section of the Season 1 DVD) or the Jehovah's Witnesses (according to Christopher McCulloch's blog), though his bizarre appearance often sabotages his attempts at evangelism. Due to his newfound faith, he is now a pacifist which seems to confirm that he is a Jehovah's Witness.
• Dr. Entmann (voiced by Stephen DeStefano): A tiny man that was left abandoned in a nuclear fallout shelter. In his previous heroic incarnation he was 15 feet tall, flabby, and curly haired and went by the name Humongeloid. Brock Samson finds Dr. Entmann in a disused and abandoned lab below the Venture Compound, where he had been trapped for some 30 years, ever since an experiment to shrink him went disastrously wrong. Dr. Entmann moves in with Action Man, and is later killed when Action Man crushes him by accident.
• Swifty (voiced by Brendon Small): An African-American boxer, and former bodyguard to Dr. Jonas Venture. In flashbacks, Swifty is shown using a pair of jet-powered boots. He currently suffers from dementia from years of boxing and is employed as a janitor on Spider-Skull Island.
• Hector (voiced by Brendon Small): A Hispanic boy and childhood friend of Rusty Venture. Seen in a flashback, he used an Aztec calendar to prevent an arrow from injuring Jonas Venture. Hector then joined the original Team Venture as Rusty's companion. However, as revealed in "Powerless in the Face of Death", in the present day Rusty has no recollection of Hector or their adventures together. Hector reveals that he has been living in a part of the Venture compound closed off by Rusty years prior, unaware that it had been closed, or that Jonas Venture had died, at which point Rusty unceremoniously evicts him. Hector appears to be the proxy of Hadji from Jonny Quest in the original Team Venture.
• Ook Ook: A cave man-like member of the team. In the present day, Ook Ook's body is encased inside a block of ice for unknown reasons.

The Guild of Calamitous Intent

The Guild of Calamitous Intent are the primary antagonists in the series. They are an organization of supervillains that serves as a trade union for villains, providing benefits such as health insurance and sets the rules and standards of conduct between its members and their enemies who tend to be the superheroes and super-scientists of the world. The Guild acts as a stabilizing influence on the world of super-villainy, as without it they would be unchecked free agents with no rules restricting their behavior. The Guild not only serves to organize the world's supervillains into an organized force, but it also controls and limits the villains from total mass destruction, murder, and mayhem by restricting their attacks to Guild-approved targets. Early in the series, it was led by a mysterious figure known only as "The Sovereign", and a group of villains called the Council of Thirteen. The current incarnation of the Guild is implied to be a haven for missing and/or presumed deceased rock stars. In Season 6, most of the Council of 13 is killed by the Sovereign in order to consolidate his control over the Guild and as part of a plan to defeat the supernatural, supervillain group, The Investors. After The Sovereign is accidentally killed by O.S.I., the remaining survivors of The Sovereign's purges, Dr. Mrs. The Monarch, Dr. Phineas Phage, Dr. Z, Red Mantle, and Dragoon forge a new Council of 13, surviving Revenge Society members with help from Dr. Henry Killinger after he killed the Investors in order to restore the balance between the OSI and the Guild. He declined the role of Sovereign and left control of the Guild to the council. Season six introduces the New York branch of the Guild, which is made up of the most dangerous supervillains the organization has to offer. It is later revealed that the original Guild charter does not mandate that the Council must have exactly thirteen members, and members of the Council cannot be actively arching their enemies.

The current incarnation of the Guild was apparently founded around 1959 by Phantom Limb's grandfather, but its history can be traced back to the late Victorian era, where it was a heroic organization led by Colonel Lloyd Venture, Rusty Venture's grandfather, dedicated to the protection of an enigmatic sphere known as the "ORB". The Guild then split over how to use the ORB, with Fantomas founding the Guild of Calamitous Intent (who wanted to use the ORB to control mankind) in 1910 while Lloyd founded the modern version of the OSI (who wanted to use the ORB to help mankind).

The Council of Thirteen

The governing body of the Guild of Calamitous Intent. Known members are:

The Revenge Society

A new, independent organization of villains set up primarily to oppose the Guild of Calamitous Intent; as such, a number of its members have had unpleasant dealings with the Guild in the past. Its founder is Phantom Limb, who initially created the society as his "team" to obtain the ORB for use against the Guild; however, this version of the Revenge Society was merely Phantom Limb himself along with a coffee mug named Wisdom, a toaster named Chuck, and a shoe called Lady Nightshade that he believed were real people. After escaping Guild custody later on, Phantom Limb teamed up with Richard Impossible to found the current Revenge Society, which has since had quick success in the field of villainy and they fail to kill Dr. Venture, twice in "Bright Light, Dean City". The group has effectively been broken up as of "All this and Gargantua-2".

• The Phantom Limb (Hamilton G. Fantomos) (voiced by James Urbaniak): A villain with invisible arms and legs. Although he is quite cunning and ruthless, he is also one of the more culturally refined characters in the show, judging from his interest in Persian rugs and fine cheeses. Despite his intellect, he often comes off as pretentious, and at times clueless about the repercussions of his action - as if he's too far into his 'role' to understand what he's doing. He was originally a professor at the same state college many of the show's characters had attended and had tiny deformed arms and legs, resulting in him being disowned by his family of adventurers. When Billy Quizboy was sent in by O.S.I. to spy on him, Fantomas made Billy his lab assistant, thinking he possessed a brilliant mind. During an experiment to turn his limbs to normal size, a malfunction occurred which turned Fantomas' limbs not only to normal size, but also invisible, and endowed him with the ability to kill with a mere touch. He once dated Dr. Girlfriend, but she left him for The Monarch after she grew tired of his controlling and possessive personality.
• Professor Richard Impossible (voiced by Stephen Colbert in seasons 1, 2, and "All This and Gargantua-2" Peter McCulloch in "The Terrible Secret of Turtle Bay", Christopher McCulloch in season 3, and Bill Hader in season 4): Founder of Impossible Industries, a major government contractor, and former professor to Dr. Venture, Mr. White, Billy Quizboy, and also hired Dean Venture as an intern. He holds science and the pursuit of knowledge in much higher regard than other people; at times this has made itself manifest as homicidal ruthlessness, though most of the time he's simply out of touch, causing animosity with his wife, Sally. Impossible and his cohorts are a parody of the Fantastic Four: an experiment with cosmic radiation gave them each strange abilities (this parody is referenced explicitly in the episode "Love Bheits" when it is mentioned that the Impossibles beat the Ventures in a costume contest by dressing as the Fantastic Four). Richard can stretch his body like rubber, similar to Mister Fantastic, and seems to use this power to make himself appear taller. The other members of his family have useless parodies of the other members' powers. A disheveled, depressed Richard Impossible is seen in "Pomp & Circuitry," having spent time since the party in terrible condition due to being depressed from his wife leaving him for JJ Venture, being recruited by the Phantom Limb to gain revenge on the Guild, and in the end, forming a new Guild with Phantom Limb. Richard then takes on the supervillain moniker Professor Incorrigible, but quits when he realizes his son needs him to be a father and leaves Gargantua-2 with his ex-wife and son.
• Baron Werner Ünderbheit (voiced by T. Ryder Smith): A noted member of the Guild of Calamitous Intent and former tyrant dictator of Ünderland. He wears a prosthetic metal jaw and speaks in a thick, pseudo-German accent. He blames Dr. Venture for the loss of his jaw; however, it has since been revealed that the explosion that disfigured Ünderbheit was actually caused by The Monarch. After his deposing, he is seen in "Pomp and Circuitry" panhandling outside of Impossible Industries, and again in the post-credits sequence asking to join Phantom Limb and Professor Impossible's new Guild. He is presumed dead after Gargantua-2 exploded.
  • Manservant (voiced by Christopher McCulloch): Baron Ünderbheit's servant, given to him as a birthday present while he was in college. He is so completely devoted to Ünderbheit that he almost seems to have no will of his own; he speaks in a zombie-like monotone and always appears to be staring into space. He is seen in "Pomp and Circuitry" with Baron Underbheit, panhandling outside of Impossible Industries, and by his side when the Baron tries joining Phantom Limb and Impossible's new Guild. In "Bright Lights, Dean City" he appears briefly with the Revenge Society in a new costume before Ünderbheit, to show loyalty to the Society, breaks his neck, killing him.
• Fat Chance (voiced by Christopher McCulloch): A supervillain recruited into the Revenge Society to fill up missing archetypical positions. After a scientific accident, Fat Chance's duodenum now contains a portal to another dimension from which he pulls objects that always seem to help him.
• Lyndon Bee (voiced by Christopher McCulloch) and Ladyhawk Johnson (voiced by Mia Barron): A pair of supervillains inducted into the Revenge Society. During the day Lyndon Bee transforms into a bee and at night Ladyhawk transforms into a hawk, and they are cursed to never be together except during an eclipse.
• Radical Left (voiced by Christopher McCulloch): A supervillain imprisoned at Dunwitch Asylum who has half of his body severely disfigured. Based on DC comics villain Two-Face, his personality is split between "Radical" anarchist ideas and peaceful desires more akin to a common 50's suburbanite. He is later seen as a member of the Revenge Society and later the New Council, in "All This and Gargantua-2". It is revealed in season 7 that Radical Left absorbed his nemesis Right Wing in a past encounter, meaning they each share one half of a full body, with the two occasionally playing games to decide who controls their body's actions.
• Zero (Scott Hall) (voiced by Christopher McCulloch): Originally Number One in The Monarch's forces, he is brutally beaten by Brock Samson in a stealth mission on Spider-Skull Island after his adherence to cliches while sabotaging the island caught Brock's attention. Later, he takes the name Zero, and with the original Captain Sunshine, kidnaps the world's sidekicks to pit them in battle against each other, only to be stopped by a rebellion led by Gary. He joins the Revenge Society in their robbery of Gargantua-2, but his genre blindness ultimately leads to his death, as he becomes so caught up in killing Brock that he spends minutes monologuing to him and thus allows Amber Gold to disarm him, giving Brock the chance to snap his neck.

Ünderland

Ünderland is a micronation located near Michigan. Once led by Baron Werner Ünderbheit in a dictatorship, he ruled the land and had a forced conscription for all men age 18 and a forced euthanasia at 40. Ünderland also had no prisons, as all crimes are subject to the death penalty. As a result of "Love Bheits", Ünderbheit is deposed and Ünderland becomes a democratic society.

• Girl Hitler (voiced by Mia Barron): Formerly one of Baron Ünderbheit's senior advisers, she (along with Catclops and Manic 8-ball) was "executed" for betraying Ünderbheit's confidence, although all three survived. Since Baron Ünderbheit's removal from power, she has become Ünderland's president.
• Catclops (voiced by James Urbaniak): A cyclops with a cat's face and a tail protruding from the back of his head. After their "execution" by tiger-bombs, he and Girl Hitler fled underground, where they led an ineffectual group of freedom fighters. After Ünderland's liberation, he proposed to Girl Hitler.
• Manic 8-ball (unvoiced): A human with the powers of a magic 8-ball. He was "executed" by Baron Ünderbheit for treason along with Catclops and Girl Hitler. Despite surviving the combination of tiger attack and explosion, he was captured and remained a prisoner of Ünderbheit, who used his eight-ball power for advice. Lacking a mouth, he never speaks, instead using the 8-ball messages on his chest to answer yes or no questions.
• Eunuchs (voiced by Christopher McCulloch and James Urbaniak): A pair of homosexuals who work under Baron Ünderbheit to prepare Dawn (Dean Venture) for the Baron's wedding. The thinner of the two was actually a college student from Detroit who took a semester abroad to Ünderland before being captured and conscripted as a court eunuch. He discovers that Dean is actually a boy but keeps the secret to embarrass Ünderbheit.

Imprisoned villains

• King Gorilla (voiced by Christopher McCulloch): A talking homosexual gorilla who befriended The Monarch while in jail. King Gorilla was a member of the Guild of Calamitous Intent until his imprisonment for brutal murder and rape of Mötley Crüe lead singer Vince Neil during a reality TV show. Because of his high-profile crime, the Guild turned its back on King Gorilla and has led to the villain becoming bitter and cynical towards the Guild. After kidnapping and attempting to rape The Monarch, he was moved enough by The Monarch's quest to regain Dr. Girlfriend's love that he assisted in the fellow villain's escape from prison. Though it was believed at first that King Gorilla had been killed off screen by Phantom Limb, Christopher McCulloch's LiveJournal has revealed he was supposed to return, free from prison, in the second half of the fourth season.
• Mr. Monday (voiced by Christopher McCulloch): An upperclass-esque villain with a monocle, obsessed with Monday. When The Monarch is planning his breakout for that night, Mr. Monday insists "Can't we wait until Monday?" and uses words such as "Mondaylicious!" Mr. Monday is released from prison by Phantom Limb, only to be hunted and killed by him on his private grounds in Showdown at Cremation Creek (Part I).
• Tigeriffic (voiced by Paul Boocock) A former supervillain with superhuman strength and tiger-like abilities.
• White Noise (voiced by Brendon Small) A smoking, racist former television repair-man, White Noise was transformed while repairing a TV that was still plugged into a live socket. He is concerned about The Monarch's criminal organization being "racially mixed", and doesn't want his pure white blood to be muddied. The Monarch then questions whether he even has blood, and how he knows he's even white. He speaks with a Southern dialect. During The Monarch's escape, he was supposed to aid by taking out the guards, along with Dr. Septapus. He is also hunted and fatally shot by Phantom Limb on his private grounds.
• Dr. Septapus (voiced by Christopher McCulloch): Another one of The Monarch's criminal cohorts while in prison, Dr. Septapus has seven limbs on his body. Four arms on his sides, one arm from his chest, and two legs. During The Monarch's escape, he was supposed to aid by taking out the guards, along with White Noise. He is released from prison, only to be hunted by Phantom Limb on his private grounds. He is shot down from a tree, and then shot again on the ground.
• Tiny Joseph (voiced by Doc Hammer): Although he originally appeared as one of The Monarch's henchmen in a dream sequence in "A Very Venture Christmas", he later appeared as The Monarch's cellmate. He is only a few inches tall, and inscribes a message upon a Microdot, which is to be carried out by a butterfly for The Monarch. He was also used as a projectile in The Monarch's makeshift prison dartgun.
• Teddy (voiced by Christopher McCulloch): A criminally insane supervillain with severe burns who once provided the voice for a Teddy Ruxpin-like toy, imprisoned in the Dunwitch Asylum for the Criminally Insane after hugging Ronald Reagan too hard. The boys and Hatred first use the toy to trick their father into thinking he has been kidnapped by Zeus in "Any Which Way but Zeus", and then Hank and Dermott use the same toy to trick their father into thinking he is still talking to Teddy in "Momma's Boys" by using a prepaid cellphone to keep him occupied while they sneak out of the house. When Venture discovers part of the ruse, he assumes Teddy is in danger. Hank, Dermott, Gary, and H.E.L.P.eR try to get into Dunwitch to talk to the original Teddy, but fall into Myra Brandish's coup attempt. Teddy later escapes and saves Dr. Venture and Sgt. Hatred from certain death when their car falls into a ravine on the way to "Bygolly Gulch".
• Cuckoo Clocker (voiced by Christoper McCulloch): A supervillain imprisoned at Dunwitch Asylum who has a cuckoo clock door in his head.
• Big Time: A supervillain imprisoned at Dunwitch Asylum who has a clock face tattooed on his face and his moustache resembles two clock hands. Both he and Myra Brandish believe he has powers over time.
• Maybe Man (voiced by Christopher McCulloch): A supervillain imprisoned at Dunwitch Asylum who Myra Brandish asks to place Dean in her womb so she may finally give birth to him, although he only responds with "maybe".

Fraternity of Torment

The Fraternity of Torment is one of a handful of supervillain organizations other than the Guild of Calamitous Intent. The group was largely made up of disenfranchised men shunned by society for their various physical defects. They were frequently the antagonists to Team Venture during the 1960s, and it is shown that Jonas and his team often seemed to merely be tormenting and bullying them for fun rather than fighting them out of any sense of justice. The remnants of the original group appear in "Now Museum, Now You Don't", but it is stated they still have some level of presence in the world of organized supervillainy alongside the "Peril Partnership".

• Scaramantula (voiced by Toby Huss): An Italian spider-themed supervillain themed after the James Bond villain Scaramanga. He has eight fingers on his right hand and a partial spider mask on his face complemented by his eyebrows and moustache as a full set of eight legs. He owned Spider Skull Island until an unsuccessful kidnapping of Rusty Venture results in their defeat by Team Venture, as Dr. Venture has infiltrated the group posing as "Dr. Fanadragon" whose backstory claimed a supernumerary nipple caused exclusion in his hometown. After Dr. Venture reveals his identity, the Fraternity is defeated by Team Venture and Scaramantula escaped, and set off a self-destruct sequence that ultimately failed, resulting in Spider Skull Island's annexation into Venture Industries. In the present day, Scaramantula has retired from supervillainy and is in top shape having exercised on Spider Skull Island's escape path many times. After seeing what has been done to his former home, he assists Brainulo in taking revenge, and ultimately escapes another death at the hands of the self-destruct sequence.
• Brainulo (voiced by Christopher McCulloch): A supervillain from a thousand years in the future claimed to have been trapped in the year 1969 after Dr. Jonas Venture destroyed his means of returning. With his superior intellect and mental powers, he controlled a giant robot known as Futuro. During the attack on Spider Skull Island, Brainulo took control of Futuro, but the Humongoloid knocks it over, crushing Brainulo. In the present day, Brainulo is revealed to be a paraplegic and it appears he has become senile, but the senility is all an act to take revenge on Dr. Venture and his offspring. He preys on the insecurities and fears of those at the Jonas Venture Museum's opening party, hoping to cause a riot, but when he fails he attempts to take control of Futuro one last time, but the attempt shorts his own brain, resulting in actual senility. He turns up again in the lobby of Impossible Industries in "Bright Lights, Dean City" as an apparent applicant to the Revenge Society; however, given that he is merely sitting still and staring, he may have simply wandered in.
• Manotaur: A supervillain possessing superstrength and having been made an outcast due to his size. During the flashback in "Shadowman 9: In the Cradle of Destiny", The Monarch claimed to be "Manotaur" to avoid retaliation from Phantom Limb after he seduced Dr. Girlfriend. In the end of the episode, it is revealed the Manotaur is real and had since retired into a job with the MTA whereupon he is killed by the still living Phantom Limb.

Peril Partnership

The Peril Partnership is another supervillain union based out of Toronto. It is one of several rival organizations to the Guild of Calamitous Intent. Its members can be distinguished by their wearing the letters 'PP.' In season 7, it is revealed that the Peril Partnership has infiltrated the Guild. However, it is revealed that this is actually a splinter group made up of some of the Peril Partnership's American members, hoping to cause a war between the Guild and Peril Partnership so that they can take over as the dominant super villain organization.

• Tiger Shark (voiced by Christopher McCulloch): A shark-themed supervillain who is the only known member of the Peril Partnership. He appears in "Any Which Way But Zeus" to participate in the think tank to find everyone's kidnapped henchmen and sidekicks. He reveals he previously fought Brock Samson during Samson's time in O.S.I., though his vendetta is more personal since he found Brock in bed with his wife. Brock half-heartedly apologizes and hints his wife lied to him about being married.
• The Creep (voiced by James Adomian): The leader of the Peril Partnership splinter cell. The Creep was originally an O.S.I agent known as Mission Creep, but was discharged after he wiped out an entire Boy Scout troop while securing a mountain fortress, claiming that he mistook them for enemy combatants. He refused to join the Guild due to their rules and by-laws, and instead joined the Peril Partnership, only to again find himself chafed by their code of conduct. Finally, he established a splinter cell of equally disgruntled villains, planning to provoke a war between the Guild and the Partnership. He then made a habit of killing Guild villains for sport and taking their signature tools or gimmicks as prizes, as he planned to weaponize them against the O.S.I after taking out both the Guild and the Partnership. He is tracked down by the Monarch and 21 on orders from the Guild and O.S.I, and he forces them to play a deadly game of Lawn Darts, ending when he accidentally kills himself while distracted by Dr. Venture and Billy Quizboy appearing from Grover Cleveland's Presidential time machine.
• Blind Rage (voiced by Brendon Small): A blind, pro wrestling-themed villain who is part of the Peril Partnership splinter cell. He is sent to blackmail the Council of Thirteen, but is rebuked. Later the same day he is hunted down by Red Death, who knocks him out and ties him to the subway train tracks (but not telling him if the train is on the track he is tied to), leaving him to either be run over or survive and deliver a message not to threaten the Guild. Whether or not he survived is unknown.

S.P.H.I.N.X.

Originally a terrorist organization that was the primary adversary of the O.S.I. 20 years ago until its defeat in the Pyramid Wars of 1987. The Pyramid Wars began when S.P.H.I.N.X. seemingly claimed credit for the Movie Night Massacre on Gargantua-1, in which Jonas Venture Sr. and many others perished, but the organization was actually framed by the Sovereign using S.P.H.I.N.X. Commander's form. Several members of the O.S.I. who were disillusioned with its ineffectual bureaucracy decided take up the S.P.H.I.N.X. mantle, along with their leftover equipment, to create an organization to deal with rogue supervillains. At the end of season 4 and the beginning of season 5, the members of S.P.H.I.N.X. who were formerly O.S.I. agents are redrafted into O.S.I., leaving the former Henchman 21 as the only S.P.H.I.N.X. operative. Gary tries to recruit new members, and accidentally reunites the original S.P.H.I.N.X. members. Knowing that their S.P.H.I.N.X. loyalty chips will soon dissolve and kill them, they dedicate themselves to a final suicide attack against the O.S.I. S.P.H.I.N.X.'s rented headquarters space within the Venture compound is blown up in the season 5 episode "S.P.H.I.N.X. Rising", forcing Gary to live in the Venture's backyard. The original remaining S.P.H.I.N.X. members are:

• Michael/SPHINX Commander (voiced by Christopher McCulloch): A fairly tall man who can't control the volume of his voice. He has been stalking his former lover Theresa, the Countess. Gary forbids him to use his former name "SPHINX Commander" because Gary is now the leader, so Michael calls himself "Mister Daddy Warlord of the Children of the Corn". He later usurps Gary's position and kidnaps Hank, who is using the Countess' old power suit. He is later killed by Brock after refusing to hand over Hank.
• Theresa/The Countess: SPHINX Commander's former second-in-command and lover, a parody of the Baroness. Her powered armor suit grants its wearer enhanced strength and mobility. Hank adopts the suit, but since it was designed for the Countess it makes Hank look and move like a woman. It has a feature that prevents the wearer from harming the SPHINX Commander. After SPHINX is defeated, Hank keeps the power suit and wears it all the time. Molotov Cocktease steals the suit in "O.S.I. Love You", and it is destroyed by Brock Samson in order to fake Molotov's death.
• Wind Song (voiced by Tim Meadows): A parody of Storm Shadow, Wind Song is an African American ninja member of the original S.P.H.I.N.X. He has taken to forming a family and wearing Coogi sweaters inspired by Cliff Huxtable during his retirement.
• Diamond Backdraft (voiced by Larry Murphy): A former member of S.P.H.I.N.X. who was the group's flamethrower and snake-handling operative.

Other supervillains

• Storm Front (voiced by Christopher McCulloch): A weather controlling supervillain who protests to having to have his powers temporarily taken away for the think tank in "Any Which Way But Zeus". He claims he will not harm anyone, as his powers are purely precipitation based.
• Crime-o-dile: A crocodile-themed supervillain previously killed by Captain Sunshine after he fell into his own crock-pit that was set on fire. A henchman appears in a support group attended by 21 and 24 after the imprisonment of The Monarch.
• Scorpio (voiced by Christopher McCulloch): Another member of Captain Sunshine's rogues gallery who is scorpion-themed. He later appears in Sgt. Hatred's old home in Malice, having become Princess Tinyfeet's new lover.
• Mantilla (voiced by Nina Arianda): Real name Debra “Debbie” St. Simone. She is the daughter of Bobbi St. Simone and Force Majeure. She is an ex-girlfriend of The Monarch and is implied to be the egg donor and biological mother of the Venture Bros. She appears to have the ability to turn herself and her clothes invisible due to biological engineering. She also appears to have vast matter and energy manipulation powers, but the nature of these is unclear. She is the leader of the apparent upstart villain guild and smartphone app known as ARCH.

The Impossibles

• Sally Impossible (voiced by Mia Barron): Richard's estranged wife. She has invisible skin which leaves her muscle tissue visible and requires all her concentration to keep her skin visible. Sally developed, and still maintains, a crush on Dr. Venture, who was repelled when he discovered her condition. Richard has implied that she has been repeatedly unfaithful and that her newborn son might have been fathered by someone else. This is a reference to the Invisible Woman's relationship with the Sub-Mariner, who has pursued her romantically from their first encounter. Eventually, it came to the point where Richard was keeping Sally practically as a prisoner in their home and keeping her under constant guard, accurately suspecting that she wanted to run away from him. Sally has been dating Jonas Venture Jr. and resides on Spider Skull Island with the rest of the Impossibles, sans Richard and Cody, though it is hinted that she and JJ are having troubles due to the latter's inability to commit. In "All this and Gargantua-2", however, her and JJ's strained relationship finally breaks and she decides to leave with Rocket and Richard, though she implies that she and Richard's relationship will be one of shared custody over Rocket rather than anything romantic or loving.
• Rocket Impossible: Sally and Richard's newborn son. Thus far, he has not displayed any sort of superpowers or genetic mutations.
• Ned (voiced by Christopher McCulloch): Sally and Cody's cousin living with down syndrome, who has been transformed into a "giant callus" with 3-inch-thick (76 mm) skin. He lived with Sally, Rocket and J.J. on Spider-Skull Island for some time, but his whereabouts during the events of Gargantua-2 were unknown. He was later seen attending J.J.'s funeral with the rest of his family.
• Cody (voiced by Christopher McCulloch): Sally's brother. Bursts into flames when exposed to oxygen. He cannot control this painful reaction, so he is kept in an air-tight container. As a result, he is usually in a state of unconsciousness. In "Bright Lights, Dean City", Professor Impossible is revealed to have been using an imprisoned Cody to provide clean energy to Impossible Industries, an act which Phantom Limb describes as being "the most deliciously evil thing [he'd] ever seen", though the true evilness of it seems to be lost on Professor Impossible. His fate after being freed from Impossible Industries is unknown.

Jonny Quest characters

• Action Johnny/Jonny Quest (voiced by Brendon Small): Since the death of Dr. Benton Quest, he has been secreted away within the Quest Bathysphere, living in isolation and feeding (when possible) his addiction to narcotics, as shown in the episode "Twenty Years to Midnight". He is fooled into handing over a piece of Dr. Venture Sr.'s machinery after being bribed by the Captain and Jonas Jr., an act that Jonas Jr. later regretted. He has sobered up, but is still a high strung nervous wreck due to his many psychological issues resulting from his father's irresponsible parenting. In "The Buddy System", Johnny claims that "fathers are caring and protective men, and I don't have one of those". In the same episode, Johnny also expresses the desire to free Dean from his father but is stopped mid-sentence by Brock. He also implies that he staged several crimes to spite his father, including the murder of their dog Bandit. He has since shown to become much better in "Self Medication" as well as more functional and social, off-handedly mentioning that he had gone on a date with Velma Dinkley which resulted in him contracting herpes. In "The Terminus Mandate" it is revealed that he is living in a rehab facility, and he finally is able to make peace with Dr. Z.
• Race Bannon (voiced by Christopher McCulloch): Brock's friend from the Office of Secret Intelligence, where he once worked as a torturer. Died after jumping from a jet that Nat King Cobra's Snake Men were piloting while retrieving the Goliath Serum. He carries various spy gadgets reminiscent of those carried by James Bond.
• Hadji Singh (voiced by Jackson Publick): Another reference to a Jonny Quest character, he is now a manager working with Jonas Jr. He is seen also taking care of Johnny, while worrying that if he brings Johnny back home, his (Hadji's) wife will leave him.
• Dr. Z (voiced by Christopher McCulloch): A reference to a recurring villain "Dr. Zin" in the Jonny Quest franchise, he was featured in the episode "The Buddy System" in which he was to be a special guest star in a stage show featuring Action Johnny. The show was being performed as part of "Rusty's Day Camp for Boy Adventurers." Upon seeing his old nemesis, Johnny panics and has a mental breakdown. Sergeant Hatred, having interrupted the show with what he thought was a routine arching, greets Z with a hand shake, saying "The Dr. Z! Aw man, I love your work." In "Self-Medication" Dr. Z was confronted by Action Johnny, Dr. Venture, and a group of former "Boy Adventurers" to accuse him of the murder of their therapist. However, Dr. Z was innocent and the group discover that he is married. During a peaceful dinner Dr. Z advises the former "Boy Adventurers" that they need to grow up and stop living in the past, revealing that he feels that he had wasted his life and wished he and his wife could have had a normal marriage. In "Pomp and Circuitry", one of the silhouetted members of the Council of 13 looks and sounds a lot like Dr. Z. Appears to be a homage to Fu Manchu, an evil genius from a series of novels by English author Sax Rohmer. In "What Color is Your Cleansuit?" Dr. Z appears in an old Guild PSA to warn against the dangers of blundering henchmen. In "Bot Seeks Bot", Dr. Z is confirmed to be a member of the Council of 13. He is a member of the new Council of 13 in season 6, having survived the Sovereign's purge of the old Council.
• Mrs. Z (voiced by Seth Green): Dr. Z's wife of many years after he retires from supervillainy. She says that she was in fact Dr. Z's beard until the two fell in love, although it was much too late to form a family.

Therapy group members

• Lance (voiced by Seth Green) and Dale Hale (voiced by John Hodgman): The Hale Brothers were previously famous boy detectives until the murder of their father, the reason for their therapy, particularly Dale who cannot get over the sight of seeing their father dead. It is hinted that they are the perpetrators, as Lance continually dismisses that their fingerprints were on the gun that was used to murder their father due to their sleuthing, and later, when Dr. Venture accuses them of doing so, Lance quips that it was never proven and Dale goes into hysterics believing that Dr. Venture knows the truth. It is implied that the murder was driven by Lance's desire to get at their inheritance, only to discover that their father's money would all go to the Boy Detective Academy, leaving them with nothing but a car to show for their crime, though they both cherish the vehicle. They are parodies of the Hardy Boys and the Menéndez brothers.
• Ro-Boy Z (voiced by Christopher McCulloch): A robotic boy who has abandonment issues due to his creator/father and psychopathic tendencies due to a life of fighting giant robots. He also has anger issues when he sees other robots, leading to apparent pyromaniacal tendencies. He eventually gets adopted by Dr. Z and his wife Mrs. Z, allowing the couple to fulfill their familial desires and giving Ro-Boy a way to move on from his creator.

The Super Gang

• Chuck Scarsdale/Captain Sunshine (voiced by Kevin Conroy): A sunlight-powered superhero previously mentioned by The Monarch in reference to having his henchmen return the charred remains of Wonder Boy to him. Captain Sunshine, appearing in person in the episode "Handsome Ransom", has since sworn revenge on The Monarch and thwarts his plans to get a ransom for Hank and Dean from Dr. Venture when he takes Hank away, inducting him as his new sidekick and ward Wonder Boy. It is hinted that Captain Sunshine has pederastic tendencies towards the various boys he takes as his ward and Wonder Boy, although Jackson Publick has confirmed that this is not the case. In actuality, the various dangerous situations Scarsdale had to face as the original Wonderboy resulted in him developing an apparent case of Peter Pan syndrome, living out the childhood he never had through his colorful toy-filled mansion and living vicariously through his wards. Coupled with his guilt over the death of the 3rd Wonder Boy and his apparent habit of literally throwing criminals into prison rather than handing them over to the authorities, Scarsdale is painted as a dangerously out-of-touch man in the vein of older superheroes. He is the lead anchor of the Action 5 News Team, but leaves his post at the evening broadcast when The Monarch tries to re-kidnap Hank, despite being powerless at night. In the ensuing conflict, Captain Sunshine is exposed to a device Dr. Mrs. The Monarch created to reproduce his sun powers, intended to be his one weakness. Instead, the device repowers him and he rallies to defeat The Monarch and his minions, only to be disappointed when Hank chooses to step down as Wonder Boy and return home. In "Any Which Way But Zeus", Red Mantle claims he was not Captain Sunshine's archenemy, but the original Captain Sunshine (Desmond), identifying Scarsdale as the original Wonder Boy. In "Bot Seeks Bot", Sunshine and his new Wonderboy attend the funeral of his archenemy Boggles the Clue Clown and has an emotional outburst over the death of his long-time archenemy.
  • Desmond (voiced by Doc Hammer): Captain Sunshine's butler. In "Any Which Way But Zeus", Desmond is revealed to be the original Captain Sunshine, and Scarsdale his ward Wonder Boy. Desmond also acts as Zeus to convince the various organizations to set up a series of protective laws and such for sidekicks.
  • Wonderboy (voiced by Patton Oswalt): This former Wonderboy was the first ward of Captain Sunshine. As a result of his depression from being kicked out and his failed career as an independent hero, he has turned to binge eating and joins a support group of fellow former boy adventurers for therapy. It is assumed that he is the second Wonderboy, succeeding Scarsdale to Desmond, and preceding the one killed by The Monarch, Hank, and a fifth one who appears in season 5's "Bot Seeks Bot".
  • Wonderboy 5 (voiced by Larry Murphy): Captain Sunshine's current Wonderboy, who seems more or less indifferent to the death of Boggles the Clue Clown and has to drag Captain Sunshine away when he has an emotional outburst as Boggles' coffin is lowered into his grave. He also shows himself to be a more competent detective than his mentor, almost immediately solving Clue Clown's final riddle when Captain Sunshine was utterly stumped.
• Barbara Qantas/Barbie-Q (voiced by Rachel Feinstein): Chuck Scarsdale's Australian co-anchor who resembles a Barbie doll that can spout pink flames. She is one of Zeus's captives in "Any Which Way But Zeus".
• Sam Turgen/U.S. Steel (voiced by Doc Hammer): The Action 5 News Team's sports anchor who as U.S. Steel is a superpowered and Uncle Sam-inspired hero. In "Any Which Way But Zeus", U.S. Steel expects to find Ghost Robot, unaware he was killed earlier.
• Neville Brown/Brown Thrasher: Sam Turgen's sports co-anchor who as Brown Thrasher has bird-themed powers akin to Falcon. He is one of Zeus's captives in "Any Which Way But Zeus".
• Weatherbot 5/Ghost Robot (voiced by Christopher McCulloch): The Action 5 News Team's meteorologist whose true identity is that of a robot with a ghost inside of him. It is assumed he is killed by 21 in "Any Which Way But Zeus" when 21 shatters his robotic eyes. However, in season 5's "Bot Seeks Bot", Ghost Robot is alive and well, and he is deputized by the O.S.I. to aid in their undercover mission to discover the identities of the Council of Thirteen, by going on a date with Vendata as robotic Guild member Galacticon. Ghost Robot's interest in having fingers and the appearance of the real Galacticon jeopardize the mission, resulting in the death of Vendata.