Buttonbush is a common name for several plants and may refer to:
- Cephalanthus, a genus of shrubs or small trees in the madder family, Rubiaceae, especially:
- Cephalanthus occidentalis, the common Cephalanthus species in eastern North America
- Conocarpus, a genus of two species of dense multiple-trunked shrubs or small to medium-sized trees in the family Combretaceae, native to tropical regions
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