Ultimate Marvel

In the Ultimate Marvel Universe, Doctor Cornelius plays a much larger role than his mainstream counterpart. He first appeared in the Ultimate X-Men story arc Return to Weapon-X.^[5]

In this version, Doctor Cornelius along with his benefactor, Colonel John Wraith heads up the Weapon X Program. Unlike his benefactor though, he does not seem to harbor any anti-mutant sentiments, but he merely wishes to conduct experiments on mutants to indulge his own curiosities. The Weapon X Program is sanctioned by S.H.I.E.L.D. during the Gulf War and results with the creation of Wolverine, their greatest achievement ever. After Wolverine escapes, Weapon X captures several other mutants to be his replacements and eventually captures the X-Men as well. In their captivity, Cornelius augments the Beast's natural abilities along with giving him a keen sense of smell. This procedure causes Beast to transform even more by growing blue fur all over his body and growing claws on his hands and feet. During the breakout, Wraith shoots Xavier and Cornelius, aided by Beast, manages to save him. After Wraith is killed by Nick Fury and Weapon X is shut down by S.H.I.E.L.D., Cornelius' whereabouts are unknown. It is not confirmed if he has anything to do with the rogue Weapon X agents led by Tara who hunt Wolverine all over Manhattan and participate with the coup against the President of the United States.^[5]

Later, he recruits the quadriplegic Lady Deathstrike and offers her a chance of revenge against Storm, the person who is responsible for her present condition. He splices some of Wolverine's DNA with hers which gives her a healing factor that is twice as fast as Wolverine's and also bonds her shattered body with adamantium. Cornelius' true objective however is to capture Wolverine since he is accompanied by Storm at that time and he uses that fact to manipulate Deathstrike. His attempts, however, end in failure with Deathstrike being captured and imprisoned in the Triskelion and his chopper being blown up. He is presumed dead.^[6]

It was revealed that he survived the helicopter crash but has been horribly disfigured. He is responsible for Sabretooth's latest attack on Wolverine in order to gain a tissue sample. The attack works and Cornelius is shown planning to use the flesh to clone a more compliant Wolverine.^[7]

In Ultimate Origins, it is revealed that Cornelius' experiments on Wolverine created the mutant gene, which he claims is how humanity will survive.^[8][9]

Apart from the scarring, the Ultimate Marvel version of Doctor Cornelius resembles Professor Thornton (the original Director of the Weapon X project in the mainstream universe).

Television

• Abraham Cornelius appears in X-Men: The Animated Series. His voice is first heard in the season 2 episode "Repo Man" and later in the season 3 two-part premiere "Out of the Past", which reuses footage from "Repo Man".
• Abraham Cornelius appears in Wolverine and the X-Men, voiced by Jim Ward. In the episode "Past Discretions", he learns that Wolverine is in the area where Weapon X is located. Cornelius contacts Professor Thornton and is given orders to send Sabretooth to attack Wolverine. In the episode "Stolen Lives", Cornelius and Professor Thornton have Sabretooth and Maverick abduct Christy Nord.

Film

• Abraham Cornelius makes a non-speaking cameo appearance in Hulk vs Wolverine.
• Abraham Cornelius appears in X-Men Origins: Wolverine, portrayed by David Ritchie. This version is an associate of William Stryker.

Video games

• Abraham Cornelius appears in X2: Wolverine's Revenge, voiced by Don Morrow. This version of the character is far more sympathetic than the mainstream and seen as a Weapon X employee alongside Carol Hines. Both of them are sent on their way when Logan confronts Professor Thornton. When Wolverine returns to the Weapon X facility to find the cure for the Shiva Strain Virus (which acts as a failsafe implanted in Weapon X test subjects), he manages to find Abraham Cornelius and Carol Hines at the Void (a maximum security detention center for mutant criminals similar to the Vault) where they end up giving Wolverine the Part A info for the Shiva Strain Virus cure. Due to the Void Shield blocking Wolverine's contact with Professor X as Abraham Cornelius stated that the Void Shield prevents any psychic links to anyone, Wolverine ends up having to head outside to relay the info to him. Before heading to the roof, Wolverine warns Abraham Cornelius and Carol Hines that Sabretooth is in the Void and might be looking for them.
• Abraham Cornelius appears in the video game adaption to X-Men Origins: Wolverine, voiced by David Prince. He is mentioned in work logs in the "Uncaged Edition" and is later killed by Wolverine during his escape when he tries to kidnap a young mutant girl for Stryker.