2 P.M. or 2PM may refer to:
- The time 2:00 p.m. as represented on the 12-hour clock
- 2PM, South Korean boy band
- Still 2:00PM, an EP by 2PM
- The RT-2PM Topol, a mobile intercontinental ballistic missile in Russia
- 2PM, a radio station based in Port Macquarie, NSW, Australia, currently owned by Broadcast Operations Group
- Patrick Mahomes II (born 1995), Kansas City Chiefs quarterback nicknamed "2PM"
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