| 2010 Monterrey Open | |
|---|---|
| Date | 1–7 March |
| Edition | 2nd |
| Category | WTA International |
| Surface | Hard / outdoor |
| Location | Monterrey, Mexico |
| Champions | |
| Singles | |
 Anastasia Pavlyuchenkova | |
| Doubles | |
 Iveta Benešová / Barbora Záhlavová-Strýcová | |
The 2010 Monterrey Open was a tennis tournament played on outdoor hard courts. It was the second edition of the Monterrey Open and was categorized as an International tournament on the 2009 WTA Tour. It took place at the Sierra Madre Tennis Club in Monterrey, Mexico, from March 1 through March 7, 2010.
The tournament was headlined by former world no. 1 Jelena Janković, top-ranked Slovak players, Daniela Hantuchová and Dominika Cibulková, Ágnes Szávay, and Anastasia Pavlyuchenkova. Also in the field were Anabel Medina Garrigues, Aleksandra Wozniak, and 2010 Open GDF Suez finalist Lucie Šafářová.
Entrants
Seeds
| Athlete | Nationality | Ranking* | Seeding |
|---|---|---|---|
| Jelena Janković |  Serbia |
9 | 1 |
| Daniela Hantuchová |  Slovakia |
24 | 2 |
| Anastasia Pavlyuchenkova | Russia |
27 | 3 |
| Dominika Cibulková | Slovakia |
28 | 4 |
| Ágnes Szávay |  Hungary |
31 | 5 |
| Anabel Medina Garrigues |  Spain |
34 | 6 |
| Aleksandra Wozniak | .svg.png.webp){kind=small} Canada |
35 | 7 |
| Lucie Šafářová | Czech Republic |
38 | 8 |
- Rankings and seedings are as of February 22, The seedings can change.
Other entrants
The following players received wildcards into the main draw:
The following players received entry via qualifying:
Finals
Singles
Anastasia Pavlyuchenkova defeated Daniela Hantuchová, 1–6, 6–1, 6–0
- It was Pavlyuchenkova's first career singles title.
Doubles
Iveta Benešová / Barbora Záhlavová-Strýcová defeated 
Anna-Lena Grönefeld / 
Vania King, 3–6, 6–4, [10–8]